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were unable to detect anydifference in the clinical response to inhaled bron-chodilators delivered via MDI with spacer to ven-tilated patients when ?ow rates were decreasednor when ?ow patterns were altered from deceler-ating to continuous inspiratory ? ow pro? les norwhen an inspiratory pause was introduced norwhen tidal volume was increased by 4 ml/kg(Mouloudi et al. [45] compared broad-range PCR ofmaterial dislodged from replaced orthopedic implants using vortexing and sonication(sonicate fluid) with synovial fluid culture, tissue culture and culture of sonicate fluid.The combination of sonicate fluid culture and PCR (78.5%) had a higher sensitivity thansynovial fluid (64.7%) or tissue culture (70.4%). Sebaceous glands (5G) are visiblein conjunction with the infundibulum ofthe hair follicle.

Aspirin in theprimary and secondary prevention of vascular disease:collaborative meta-analysis of individual participant datafrom randomized trials. Anticonvulsant drugs have been assayed by microdialysis to confirmabsorption and delivery (5)

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